How do I make a PyQt app executable?

Yes , it is possible to compile Python scripts into standalone executables. PyInstaller can be used to convert Python programs into stand-alone executables, under Windows, Linux, Mac OS X, FreeBSD, Solaris, and AIX.

Steps to Create an Executable from Python Script using Pyinstaller

This page describes how you can compile an existing PyQt application to a self-contained .exe on Windows.