It doesn’t matter when you’re mining with your PC, during the day or during the night, components degrade either way. As far as if it’s safe to let your PC running all night long: Yes . It’s most profitable when mining rigs are run 24/7, just like all the servers.
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The short answer is yes , your power usage will go up a decent amount. The power consumption of your PC will greatly increase by mining for Bitcoins, especially if you are effectively mining with one or more GPU and mining 24/7. If you are not a full time miner, I suggest you mine at night when electricity is cheaper.19 Haz 2021
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